Photo: Ronald Martinez / Getty Images Sport / Getty Images
The San Antonio Spurs (16-7) are 5.5-point underdogs against the Los Angeles Lakers (17-6) at Crypto.com Arena on Wednesday, December 10, 2025. The game starts at 10 p.m. ET on Amazon Prime Video and SportsNet LA.
Watch the NBA, other live sports and more on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Use our link to sign up.
Listen to the game on News Radio 1200 WOAI
Lakers vs. Spurs Predictions for Wednesday
Our computer projections model for this encounter calls for a final score of Lakers 118, Spurs 117.
- Moneyline Pick: Lakers (-217)
- Total Pick: Under 237.5 (computer predicts 234.6 points)
- Pick ATS: Spurs (+5.5)
Recent Lakers vs. Spurs Matchups
| Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
|---|---|---|---|---|---|---|
| 11/5/2025 | Spurs | -1.5 | 227.5 | -121 | +101 | 118-116 LAL |
| 3/17/2025 | Lakers | -9.5 | 230.5 | -444 | +341 | 125-109 LAL |
| 1/13/2025 | Lakers | -4 | 221.5 | -186 | +154 | 126-102 SA |
| 11/27/2024 | Lakers | -1.5 | 227.5 | -134 | +112 | 119-101 LAL |
| 11/15/2024 | Lakers | -2.5 | 228 | -138 | +117 | 120-115 LAL |
Lakers 2025-26 Betting Trends
- Los Angeles' ATS record is 14-9-0 this season.
- The Lakers are 4-4 against the spread when favored by 5.5 points or more this season.
- Los Angeles has gone over in 16 of its 23 games with a set total (69.6%).
- The Lakers have been favorites in 12 games this season and won 10 (83.3%) of those contests.
- This season, Los Angeles has won seven of its eight games when favored by at least -217 on the moneyline.
Spurs 2025-26 Betting Trends
- San Antonio has a 10-11-2 record against the spread this year.
- The Spurs are 2-1 against the spread when an underdog by 5.5 points or more this season.
- San Antonio has gone over in 13 of its 23 games with a set total (56.5%).
- The Spurs have been the moneyline underdog nine total times this season. They've finished 6-3 in those games.
- San Antonio has won all two games it has played as a moneyline underdog with odds of +179 or longer.
Looking for NBA tickets? Head to StubHub today and see your team live.
Lakers vs. Spurs Injury Report
Lakers
Lakers:
Marcus Smart: Day-To-Day (Back)
Spurs
Spurs:
Victor Wembanyama: Out (Calf),
Jordan McLaughlin: Day-To-Day (Hamstring)
Lakers vs. Spurs Game Time and TV Channel
- Game day: Wednesday, December 10, 2025
- Game time: 10 p.m. ET
- TV channel: Amazon Prime Video and SportsNet LA
- Location: Los Angeles, California
- Arena: Crypto.com Arena
Sign up for NBA League Pass to get access to games, live and on-demand, and more for the entire season and offseason.