TCU vs. SMU Football Prediction & Odds - Sept. 20

placeholder image

The SMU Mustangs (2-1) visit the TCU Horned Frogs (2-0) at Amon G. Carter Stadium on Saturday, September 20, 2025.

Watch college football live without cable. Stream ACC, SEC, ESPN and more with Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Sign up today and start watching college football games now.

TCU vs. SMU Matchup Info

  • Game date: Saturday, September 20, 2025
  • Game time: 12 p.m. ET
  • Location: Fort Worth, Texas
  • Venue: Amon G. Carter Stadium
  • TV channel: ESPN2
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Stop missing games and start streaming college football right now on Fubo.

TCU vs. SMU Odds and Prediction

  • Spread favorite: Horned Frogs (-6.5)
  • Moneyline: Horned Frogs (-244), Mustangs (+198)
  • Total: 63.5 points
  • Pick ATS: TCU (-6.5)
  • Pick OU: Over (63.5)
  • Prediction: TCU 39, SMU 25

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

Looking for officially licensed gear? Fanatics has jerseys, hats, apparel, memorabilia, trading cards, collectibles and more.

TCU vs. SMU Betting Records and Insights

  • TCU has covered once in two matchups with a spread this season.
  • SMU is winless against the spread this year (0-2-0).
  • The Horned Frogs have been favored by 6.5 points or more this season once, and failed to cover the spread.
  • So far this season, each TCU game has hit the over.
  • So far this year, one SMU game has gone over the point total.

Sponsored Content

Sponsored Content